“…to compensate for the stress by acting like morphine equivalents and the endorphins themselves limit your physiological functions in a protective way, sort of like a localized kind of hibernation. So the naloxone or naltrexone will clear those out. Sometimes in two or three days, you can see a person come out of depression or a lethargic state or there was a study in California of demented people who were given very big doses of naloxone for several days or several weeks and their dementia improved just by blocking the endorphins.”